Part One
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The Renaissance began to utilize the classical ideas and forms again in the arts, following the cultural ideals of continuation with the ancient world. Over a period of a few short years, an architect (Brunelleschi), a sculptor (Donatello) and a painter (Masaccio) carried out a revolutionary transformation in Florence of the conceptions and the functions of creative activity. Art was no longer a "mechanical activity", or a sort of handcraft, but a "liberalis", or rather, an intellectual exercise. This transition was confirmed by the publication of several theoretical works by Leon Battista Alberti: "De pictura" (1436) dedicated to Filippo Brunelleschi, "De re aedificatoria" (1452) e "De statua" (1464).
Art became an instrument of knowledge and research into reality; it was a real science based on rational theoretical foundations, like the rules of perspective. The key-concept of the "imitation of nature" was based on the contrast between classical and Byzantine traditions but should also be understood as the mathematical and geometrical organization of visual data (the object of the painting) within a given space (a panel or wall to be frescoed).

This artistic rebirth (through the patronage of the rich) spread and developed, reaching the greatest heights of "Classicism" with Bramante, Michelangelo and Leonardo. The artists that followed Raphael and Michelangelo (who as a boy lived in Lorenzo the Magnificent's house and in the gardens of St. Mark ) with Poliziano and other humanists) developed Mannerism into a nonconformist search for pure originality as a reaction to the anxiety that transpired behind the veils of Classicism.